Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE. Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE generating glycerophospho-N-acyl ethanolamine (GP-NAE, an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.
应用类型
WB, IF/ICC
免疫原
Recombinant fusion protein of human ABHD4(NP_071343.2).
