Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA, a process in which RNA or DNA is directly imported into lysosomes in an ATP-dependent manner, and degraded. Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis. In vitro, mediates the uptake of linear DNA more efficiently than that of circular DNA, but exhibits similar uptake efficacy toward RNA and DNA. Binds long double-stranded RNA (dsRNA (500 - 700 base pairs, but not dsRNA shorter than 100 bp (By similarity.
应用类型
IF/ICC
免疫原
Recombinant fusion protein of human SIDT2(NP_001035545.1).
