Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.
应用类型
WB
免疫原
Recombinant fusion protein of human MVB12A(NP_612410.1).