Interacts with TGF-beta receptor type-1 (TGFBR1 and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.
应用类型
WB
免疫原
Recombinant fusion protein of human VEPH1(NP_078897.2).
