Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
应用类型
WB
免疫原
Recombinant fusion protein of human CUEDC2(NP_076945.2).
