The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
应用类型
WB, IHC, IF/ICC
免疫原
A synthetic peptide of human ATG16L1(NP_110430.5).
