- 中文名称
SPAM1 polyclonal antibody
- 英文名字
- SPAM1 polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS6737
- 产品报价
- ¥询价/50ul

- 产品说明书
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- 产品新闻

- 背景资料
- Hyaluronidases (HAases or HYALs) are a family of lysosomal enzymes that are crucial for the spread of bacterial infections and of toxins present in a variety of venoms. HYALs may also be involved in the progression of cancer. In humans, six members of the hyaluronidase family have been identified. These proteins are significant in the degradation of hyaluronic acid (HA), which is present in body fluids, tissues and the extracellular matrix of vertebrate tissues. HA keeps tissues hydrated, maintains osmotic balance and promotes cell proliferation, differentiation and metastasis. HA is also an important structural component of cartilage and other tissues and acts as a lubricant in joints. SPAM1 (sperm adhesion molecule 1), also designated Hyal-PH20 or sperm surface protein PH-20, was formerly referred to as HYAL1 (HYA1). The current nomenclature references the functional hyaluronidase activity of SPAM1 to permit acrosome-intact sperm to penetrate through the HA-rich cumulus cell layer surrounding the oocyte. SPAM1 is also implicated in intracellular signaling and zona pellucida binding. SPAM1 is found in the epididymis and in testis, more specifically in plasma and acrosomal membranes of sperm. SPAM1 is a structurally unique hyaluronidase in that it is a GPI-anchored protein.
- 应用类型
- WB, IHC, IF/ICC
- 免疫原
- Recombinant full length Human SPAM1.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse, Rat
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利

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