- 中文名称
TNFAIP6 polyclonal antibody
- 英文名字
- TNFAIP6 polyclonal antibody
- 供应商
- Bioworld
- 产品货号
- BS6310
- 产品报价
- ¥询价/50ul

- 产品说明书
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- 产品新闻

- 背景资料
- The TSG6 gene is transcribed in normal fibroblasts and activated by binding of the cytokines TNFα and IL-1 at AP-1 and NF-IL6 sites in its promoter. TSG-6 is a glycoprotein and a member of the hyaluronan-binding protein family, which includes cartilage link protein, proteoglycan core protein and the adhesion receptor CD44. TSG-6 is highly homologous to CD44, particularlynin the hyaluronic acid-binding domain. TSG-6 is found in TNF-treated cells; its expression is rapidly activated by TNFα, IL-1 and lipopolysaccharide in normal fibroblasts, peripheral blood mononuclear cells, synovial cells and chondrocytes. The presence of TSG-6 in synovial fluid suggests a possible role in rheumatoid arthritis. TSG-6 forms a stable complex with components of the serine protease inhibitor, inter-α-inhibitor (IαI)). TSG-6 potentiates theninhibitory effect of lαl on the protease activity of plasmin. Through theirncooperative inhibitory effect on plasmin, TSG-6 and lαl can modulate thenprotease network and thus inhibit inflammation.
- 应用类型
- WB
- 免疫原
- Recombinant full length Human TNFAIP6.
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse, Rat
- 保存建议
- Store at 4
- 其他
- Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利

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