Auristatin E CAS:160800-57-7产品的分子式为C40H69N5O7,分子量为732.02523,纯度为0.95,溶解度为
产品描述
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; it is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent. Auristatin E inhibits tubulin polymerization(1). Auristatin E-antibody cunjugates have proven to be successful anticancer agents.(2) Ref. 1. Pettit et al. Anticancer Drug Des. 1995 10:529. Ref. 2. Doronina et al. Nature Biotechnol. 2003 21:778. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.