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中文名称

重组Maspin,人

英文名字
RecombinantMaspin,Human
供应商
Bioworld
产品货号
BK0124
产品报价
¥询价/10ug
产品说明书
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产品新闻
背景资料
Maspin is a non-inhibitory member of the serpin superfamily, a group of 40-60 kDa serine protease inhibitors. Maspin was discovered in 1994 and has been identified in prostate, thymus, testis, intestine, tongue, and lung. Recently Maspin received a great deal of attention due to its potential apoptotic role in cancers. Maspin expression predicts a better prognosis for several types of carcinomas including breast, prostate, colon, and oral squamus cell carcinoma. The level of Maspin is also inversely correlated to VEGF-A, an angiogenic factor. Researchers found that Maspin may play its apoptotic role as an endogenous inhibitor of histone deacetylase I (HDAC I). Therefore, Maspin is a potential personalized marker of Non-Small Cell Lung Carcinoma (NSCLC).Recombinant human Maspin (rhMaspin) produced in E.coli is a single non-glycosylated polypeptide chain containing 375 amino acids. rhMaspin has a molecular mass of 42.1 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
序列
MDALQLANS AFAVDLFKQL CEKEPLGNVL FSPICLSTSL SLAQVGAKGD TANEIGQVLH FENVKDIPFG FQTVTSDVNK LSSFYSLKLI KRLYVDKSLN LSTEFISSTK RPYAKELETV DFKDKLEETK GQINNSIKDL TDGHFENILA DNSVNDQTKI LVVNAAYFVG KWMKKFPESE TKECPFRLNK TDTKPVQMMN MEATFCMGNI DSINCKIIEL PFQNKHLSMF ILLPKDVEDE STGLEKIEKQ LNSESLSQWT NPSTMANAKV KLSIPKFKVE KMIDPKACLE NLGLKHIFSE DTSDFSGMSE TKGVALSNVI HKVCLEITED GGDSIEVPGA RILQHKDELN ADHPFIYIIR HNKTRNIIFF GKFCSP
来源宿主
Escherichia coli.
溶解建议
Reconstituted in ddH2O at 100 μg/mL.
保存建议
Lyophilized recombinant human Maspin (rhMaspin) remains stable up to 6 months at -80
其他
Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
注意
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