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中文名称

重组IFN-γ,小鼠

英文名字
RecombinantIFN-γ,Mouse
供应商
Bioworld
产品货号
BK0081
产品报价
¥询价/100ug
产品说明书
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产品新闻
背景资料
Sharing 41% sequence identity with human Interferon gamma (hIFN--γ), mouse IFN gamma (mIFN--γ)is a macrophage-activating factor.The active form of IFN--γ is an antiparallel dimer that sets off IFN--γ/JAK/STAT pathway. IFN--γ signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity.While IFN--γ–induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN--γ is also implicated in resistance to NK cell and CTL responses and in immune escape in avariety of cancers.Recombinant mouse IFN gamma (rmIFN-γ) produced in E.coli is a non-glycosylated polypeptide chain of 134 amino acids. A fully biologically active molecule, rmIFN--γ has a molecular mass of 15 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary refolding and chromatographic techniques at GenScript.
序列
MHGTVIESL ESLNNYFNSS GIDVEEKSLF LDIWRNWQKD GDMKILQSQI ISFYLRLFEV LKDNQAISNN ISVIESHLIT TFFSNSKAKK DAFMSIAKFE VNNPQVQRQA FNELIRVVHQ LLPESSLRKR KRSRC
来源宿主
Escherichia coli.
溶解建议
Reconstituted in ddH2O or PBS at 100 μg/ml.
保存建议
Lyophilized recombinant mouse IFN gamma (rmIFN-γ) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmIFN-γ should be stable up to 1week at 4°C or up to 2 months at -20°C.
其他
Bioworld是专一服务于生命科学研究的专业技术型企业,Bioworld品牌创立以来拥有10000多种常规产品现货,现有8000多种现货抗体,以及其他IVD原料,蛋白等现货产品。在细胞信号通路、免疫学、蛋白组学上拥有显著优势,其抗体产品、生长因子、IVD原料等为生命科学科研工作者提供了极大的便利
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