Chemokine (C-X-C motif) ligand 2(CXCL2) is a small cytokine belonging to the CXC chemokine family that is also called macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 shares 90% amino acid sequence with CXCL1/GROα. The GRO proteins are chemotactic for neutrophils and basophils and can activate them through their CXCR1 or CXCR2 receptors.Recombinant Rat GRO-β/CINC-3/CXCL2 produced in E.coli is a single non-glycosylated polypeptide chain containing 69 amino acids. A fully biologically active molecule, rrGRO-β has a molecular mass of 7.6kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
序列
SE LRCQCLTTLP RVDFKNIQSL TVTPPGPHCA QTEVIATLKD GHEVCLNPEA PLVQRIVQKI LNKGKAN
来源宿主
Escherichia coli.
溶解建议
Reconstituted in ddH2O or PBS at 100 μg/ml.
保存建议
Lyophilized recombinant Rat GRO-β/CINC-3/CXCL2 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat GRO-β/CINC-3/CXCL2 should be stable up to 1 week at 4°C or up to 3 months at -20°C.
