- 中文名称
生物活性硬骨素Elisa试剂盒
- 英文名字
- Bioactive Sclerostin ELISA Kit
- 供应商
- Biomedica Immunoassays
- 产品货号
- BI-20472
- 产品报价
- ￥12x8tests
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Sclerostin is a 22.5 kDa secreted glycoprotein that functions as a potent inhibitor of Wnt signaling. It acts by binding to the Wnt-coreceptor LRP5/6 thus inhibiting bone formation by regulating osteoblast function and promoting osteoblast apoptosis. The Sclerostin protein consists of two flexible N- and C-terminal arms and a cystine-knot with three loops, whereas the second loop binds to the LRP5/6 complex. Sclerostin is classically considered to be a monomeric protein, but data from Hernandez and colleagues (Hernandez et al., 2014) postulate that circulating sclerostin has a dimeric configuration. In addition, it is not yet well documented if also Sclerostin fragments circulate, but the comparison of different Sclerostin ELISAs suggest that fragments exist as well (Dallas et al., 2013).
- 产品描述
- Method
Sandwich ELISA, HRP/TMB, 12×8-well detachable strips
Sample type
Serum, EDTA plasma and citrate plasma
Sample volume
20 µl / well
Assay time
2 h / 1 h / 30 min
Sensitivity
1.9 pmol/l (= 42.7 pg/ml)
Standard range
0 – 320 pmol/l (= 0 – 7 200 pg/ml)
Conversion factor
1 pmol/l = 22.5 pg/ml (MW: 22.5 kDa)
Precision
In-between-run (n=7): ≤5 % CV
Within-run (n=3): ≤ 1 % CV
Specificity
Endogenous and recombinant bioactive Sclerostin.
- 产品特点
- 保存建议
- +4°C
- 其他
- Biomedica Immunoassay(bmgrp)公司成立于1988年, 总部位于奥地利维也纳，主要致力于研究、开发和生产基于ELISA方法用于临床前研究相关标记物检测的工具。迄今为止Biomedica Immunoassay公司在心血管检测及骨代谢检测领域开发了一系列特色ELISA检测试剂盒，Biomedica Immunoassay的生产过程符合GMP/GLP指南，并符合ISO 9001:2015管理体系，有CE认证。Biomedica Immunoassay的产品根据FDA， EMEA和ICH指南进行验证，并具有验证报告。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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