- 中文名称
人Wnt通路抑制因子 Dickkopf-1 Elisa试剂盒
- 英文名字
- Human DKK1 ELISA Kit
- 供应商
- Biomedica Immunoassays
- 产品货号
- BI-20413
- 产品报价
- ¥12x8tests

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- DKK-1 is a 25.8 kDa secreted protein functioning as antagonist of the canonical Wnt signaling pathway. It is a member of the dickkopf-related protein family characterized by two cysteine-rich domains separated by a linker region. Binding of DKK-1 to the LRP5/6 co-receptor inhibits the interaction with Wnt and by forming a ternary complex with transmembrane Kremen-1 or -2, promotes the internalization of LRP5/6
- 产品描述
- Method
Sandwich ELISA, HRP/TMB, 12×8-well detachable strips
Sample type
Serum
Sample volume
20 µl / well
Assay time
2 h / 1 h / 30 min
Sensitivity
1.7 pmol/l (= 43.0 pg/ml)
Standard range
0 – 160 pmol/l (= 0 – 4102 pg/ml)
Conversion factor
1 pmol/l = 25.8 pg/ml (MW: 25.8 kDa)
Precision
In-between-run (n=9): ≤3 % CV
Within-run (n=5): ≤ 3 % CV
Cross-reactivity
Human DKK-1 only.
No cross-reactivity or interference with recombinant human DKK-2, DKK-4, Kremen-1, Kremen-2 or LRP-6 is observed.
Validation Data
See validation data tab for: precision, accuracy, dilution linearity, values for healthy donors, etc
Detection range
1.7 – 160 pmol/l (=43 – 4102 pg/ml)
- 产品特点
- 保存建议
- +4°C
- 其他
- Biomedica Immunoassay(bmgrp)公司成立于1988年, 总部位于奥地利维也纳,主要致力于研究、开发和生产基于ELISA方法用于临床前研究相关标记物检测的工具。迄今为止Biomedica Immunoassay公司在心血管检测及骨代谢检测领域开发了一系列特色ELISA检测试剂盒,Biomedica Immunoassay的生产过程符合GMP/GLP指南,并符合ISO 9001:2015管理体系,有CE认证。Biomedica Immunoassay的产品根据FDA, EMEA和ICH指南进行验证,并具有验证报告。
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- 注意
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