GSK-2190915钠盐产品是GSK-2190915 sodium is a potent and selective FLAP (5-Lipoxygenase-activating protein) inhibitor (IC₅₀ of 2.6 nM); displays good selectivity over CYP3A4, 2C9, and 2D6. In an acute inflammation setting, GSK-2190915 dose-dependently reduces LTB4, CysLTs, plasma protein extravasation and neutrophil influx induced by peritoneal zymosan injection.