BMN-673产品是BMN-673 is a potent and selective PARP1/2 inhibitor with Ki values of 1.2 and 0.9 nM, respectively. It had no effect on panels of 72 receptors, ion channels, and enzymes. BMN-673 displays selective antitumor cytotoxicity and elicits DNA repair biomarkers at much lower concentrations than earlier generation PARP1/2 inhibitors.