布里瓦尼产品是Brivanib is a potent, ATP-competitive inhibitor against human Flk-1 (VEGFR-2) and mouse Flk-1 with IC₅₀ of 25 nM and 89 nM, respectively. Brivanib also inhibits VEGFR-1 and FGFR-1 with IC₅₀ values of 0.38 and 0.148 μM. Brivanib displays antitumor activities in H3396 xenograft.