GW-441756产品是GW-441756 is potent and specific inhibitor of Trk A (tropomyosin-related kinase A) tyrosine kinase (IC₅₀ = 2 nM). This inhibition of TrkA reduces cell proliferation and enhances the effects of chemotherapeutic agents in sarcoma. GW-441756 displays >100-fold selectivity over a range of other kinases.