- 中文名称
Bcl 2 (B Cell Leukemia 2), Pro-Survival Family Antibody Sampler Kit, BioAssay
- 英文名字
- Bcl 2 (B Cell Leukemia 2), Pro-Survival Family Antibody Sampler Kit, BioAssay
- 供应商
- USBiological
- 产品货号
- B0807-02D
- 产品报价
- ￥1/1Kit
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- The Bcl-2 family consists of a number of evolutionarily conserved proteins containing Bcl-2 homology domains (BH) that regulate apoptosis through control of mitochondrial membrane permeability and release of cytochrome c (1-3). Four BH domains have been identified (BH1-4), which mediate protein interactions. The family can be separated into three groups based upon function and sequence homology: pro-surivival members including Bcl-2, Bcl-xL, Mcl-1, A1, and Bcl-w; pro-apoptotic proteins including Bax, Bak, and Bok; and “BH3 only” proteins Bad, Bik, Bid, Puma, Bim, Bmf, Noxa, and Hrk. Interactions between death-promotingand death-suppressing Bcl-2 family members has led to a rheostat model in which the ratio of pro-apoptotic and anti-apoptotic proteins controls cell fate (4). Thus, pro-survival members exert their behavior by binding to and antagonizing death-promoting members. In general, the “BH3-only members” can bind to and antagonize the pro-survival proteins leading toincreased apoptosis (5). While some redundancy of this system likely exists, tissue specificity and transcriptional and post-translational regulation of many of these family members can account for distinct physiological roles. Several phosphorylation sites have been identified withinBcl-2 including Thr56, Ser70, Thr74, and Ser87 (6).Included antibodies:B0807-02D1 Bcl 2, phosphorylated (Ser70) 20ulW, F H 28kDRabbitB0807-02D2 Bcl-2, phosphorylated (Thr56) 20ul W H 28kDRabbitB0807-02D3 Bcl-2 20ul W, IP, IHC H 28kDRabbitB0807-02D4 Bcl-XL20ul W, IP, IHC H, M, R, Mk 30kDRabbitB0807-02D5 Mcl-120ul W H 40kDRabbitB0807-02D6 IgG (HRP)100ul GoatStorage and Stability:May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot. Freeze at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- 产品特点
- 针对Bcl 2 (B Cell Leukemia 2), Pro-Survival Family Antibody Sampler Kit, BioAssay该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到Bcl 2 (B Cell Leukemia 2), Pro-Survival Family Antibody Sampler Kit, BioAssay产品后将其置于-20°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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