- 中文名称
H3S10pT11p |组蛋白H3(p Ser10,p Thr11)
- 英文名字
- H3S10pT11p | Histone H3 (p Ser10, p Thr11)
- 供应商
- Agrisera
- 产品货号
- AS16-3179
- 产品报价
- ¥询价/50ug

- 产品说明书
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- 产品新闻

- 背景资料
- When confronted with DNA damage or the lack of certain kinases like Chk1 and Aurora1, histone H3 is phosphorylated at T11, causing a reduction in acetylation of the same histone at K9 and ultimately leading to a reduction of active transcription in affected cells. When the T11 phosphorylation is combined with a typical S10 phosphorylation that is critical in chromosome condensation in metaphase, the effect on transcriptional regulation is amplified further. Phosphorylation of H3S10 is decreased by T11 phosphorylation. Thus, detection of the combined modification is critical in determining transcriptional effects, especially when contrasted against single modifications of H3.
- 应用类型
- Chromatin immunoprecipitation (ChIP), Immunofluorescence (IF), Immunohistochemistry (IHC), Western blot (WB)
- 免疫原
- KLH-conjugated synthetic peptide
- 来源宿主
- 兔
- 反应性
- Caenorhabditis elegans, 人
- 保存建议
- Store lyophilized/reconstituted at -20
- 其他
- Agrisera公司提供1000种用于植物和藻类细胞生物学研究的一抗,2000多种二抗。Agrisera公司提供的植物领域的抗体涵盖拟南芥、莱茵衣藻、蓝藻、松柏类、硅藻、大豆、大麦、蒺藜苜蓿、烟草、稻、菜豆、小立碗藓、杨树、豌豆、番茄、马铃薯、菠菜、小麦、玉米、葡萄等多个物种,此外还有水生生物类(藻类、鱼)抗体,细菌、昆虫、真菌抗体。针对植物蛋白质的保守氨基酸序列,Agirsera还独家开发了数十种通用抗体(global antibodies),这类抗体几乎可以与所有的高等植物及藻类产生免疫反应,可为研究人员提供极为方便的选择。

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