Saporin is a ribosome-inactivating protein (RIP) of type I. This monomeric RNA N-glycosidase purified from seeds of the plant Saponaria officinalis also known as Soapwort, is capable of specific depurination of eukaryotic ribosomes thus arresting protein synthesis. No ligand has been identified in saporin hence its inability to transverse the cell membrane. Due to its toxicity and stability of the structure, saporin has proven extremely useful for construction of immunotoxins.
应用类型
ELISA (ELISA), Immunihistochemistry (IHC), Immunofluorescence (IF), Western blot (WB)
免疫原
Saporin, whole molecule
来源宿主
兔
反应性
Purified saporin
保存建议
For long term stability requires storage. preferably in small aliquots at -20
