Histone H3-like centromeric protein HTR12 replaces formal H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. It is required for the assembly of kinetochore proteins, mitotic progression and chromosome segregation. Localized at centromeres in both m itotic and meiotic cells. Synonymes: CENH3
应用类型
ELISA (ELISA), Immunohistochemistry (IHC), Western blot (WB)
免疫原
KLH-conjugated synthetic peptide derived from N-terminal domain of Arabidopsis thaliana HTR12 AT1G01370 (Q8RVQ9)