Ryanodine is found naturally in the stem and roots of the plant Ryania speciosa. The Ryanodine alkaloid was first isolated as a potential insecticide but was found to act as potent paralytic on skeletal and cardiac muscles. Ryanodine inhibits SR Ca2+ release by binding with high affinity to the Ryanodine receptor (RyR) channel as a tetrameric complex.
产品描述
A Blocker of Ryanodine Receptors
产品形式
Ryanodine is found naturally in the stem and roots of the plant Ryania speciosa. The Ryanodine alkaloid was first isolated as a potential insecticide but was found to act as potent paralytic on skeletal and cardiac muscles. Ryanodine inhibits SR Ca2+ release by binding with high affinity to the Ryanodine receptor (RyR) channel as a tetrameric complex.