- 中文名称
KT5823(5 x 50 ug)
- 英文名字
- KT5823
- 供应商
- Alomone
- 产品货号
- ALO-K-250-5x50
- 产品报价
- ¥已停产

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- KT5823 is a semi-synthetic derivative of K525a. It is a potent, selective inhibitor of cGMP-dependent protein kinase (PKG) (in vitro IC50= 234 nM). KT5823 interferes at the level of the ATP binding site of the catalytic domain of PKG. The PKG are Ser/Thr protein kinase with broad substrate specificity, and expressed in; brain, smooth muscle cells, platelets, juxtaglomerular kidney cells, and endothelial cells. KT5823 triggered apoptotic DNA fragmentation in immortalized uterine epithelial cells, suggesting a regulatory role for PKG in the apoptotic process in these cells.
- 产品描述
- A Selective PKG Inhibitor
- 产品形式
- KT5823 is a semi-synthetic derivative of K525a. It is a potent, selective inhibitor of cGMP-dependent protein kinase (PKG) (in vitro IC50= 234 nM). KT5823 interferes at the level of the ATP binding site of the catalytic domain of PKG. The PKG are Ser/Thr protein kinase with broad substrate specificity, and expressed in; brain, smooth muscle cells, platelets, juxtaglomerular kidney cells, and endothelial cells. KT5823 triggered apoptotic DNA fragmentation in immortalized uterine epithelial cells, suggesting a regulatory role for PKG in the apoptotic process in these cells.
- 保存建议
- 艾美捷为您提供的Alonmone Labs原装进口的KT5823 (5 x 50 µg)产品可室温运输,建议您在收到产品后将其置于合适的温度下保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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