K252a is an alkaloid isolated from Nocardiopisis sp.soil fungi.This ATP analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50= 1.8 and 1.7 nM respectively). At higher concentrations it is also an efficient inhibitor of serine/threonine protein kinases (IC50 of 10 to 30 nM).
产品描述
A Potent Inhibitor of Protein Kinase A, Protein Kinase C, and Protein Kinase G
产品形式
K252a is an alkaloid isolated from Nocardiopisis sp.soil fungi.This ATP analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50= 1.8 and 1.7 nM respectively). At higher concentrations it is also an efficient inhibitor of serine/threonine protein kinases (IC50 of 10 to 30 nM).