- 中文名称
NaV1.4抗体(50 ul)
- 英文名字
- Anti-NaV1.4
- 供应商
- Alomone
- 产品货号
- ALO-ASC-020-50
- 产品报价
- ¥已停产

- 产品说明书
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- 购买方式
- 银行转账、电汇、支票、现金,在线支付宝及网银支付,或直接与我们电话联系400-6800-868。
- 产品新闻

- 背景资料
- Voltage-gated sodium channels (Nav) are essential for the generation of action potentials and for cell excitability. Nav channels are activated in response to depolarization and selectively allow flow of Na+ ions. The Nav channels are classified into two groups according to their sensitivity to Tetrodotoxin (TTX): TTX-sensitive and TTX-resistant channels Mammalian sodium channels are heterotrimers, composed of a central, pore-forming α subunit and two auxiliary β subunits. The expression of the α subunit isoform is developmentally regulated and tissue specific. To date, nine Nav α subunits have been cloned and named Nav1.1-Nav1. Sodium channels in the adult central nervous system and heart contain β1 through β4 subunits, whereas sodium channels in adult skeletal muscle have only the β1 subunit.nThe isoform Nav1.4, is primarily expressed in skeletal muscle.nDifferent missense mutations in the gene for the Nav1.4 are correlated with several muscular diseases such as, Paramyotonia congenital (PMC), PMC without cold paralysis, potassium-aggravating myotonia, and hyperkalemic periodic paralysis.
- 应用类型
- 经验证,该抗体可应用于WB等实验应用,也可用于IC、IFC、IH、IP等实验。
- 免疫原
- NaV1.4抗体的免疫原肽段为EDKELKDNHILNHVG(C)。此免疫原序列来源于877-891 位氨基酸残基,该序列来源于大鼠Nav1。4 (Accession编号为P15390 )。胞内环位于结构域 II和III。
- 来源宿主
- 兔
- 反应性
- 反应性:人、 小鼠、 大鼠
- 保存建议
- 艾美捷为您提供的NaV1.4抗体(50 ul)为室温运输,建议您收到产品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证,以冻干粉形式提供,可确保产品生物活性和保质期。Alomone可提供多种包装规格,灵活方便。作为Alomone Labs在中国的区域总代理,艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。

- 注意
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该页面的中文产品信息的翻译,仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前,请浏览说明书确认。
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