- 中文名称
甜菜碱/ GABA转运蛋白1（BGT-1）抗体（25 ul）
- 英文名字
- Anti-Betaine/GABA Transporter 1 （BGT-1)
- 供应商
- Alomone
- 产品货号
- ALO-AGT-004-25
- 产品报价
- ￥已停产
- 产品说明书
- 点击查看
- 购买方式
- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868。
- 产品新闻
- 背景资料
- γ-aminobutyric acid (GABA) transporters (GATs) are essential regulators of the activity in the GABAergic system through their continuous uptake of the neurotransmitter from the synaptic cleft and extrasynaptic space. Four GABA transporters (GAT1, GAT2, GAT3 and BGT1) have been identified. Betaine/GABA transporter (BGT1, SLC6A12) is a member of the Na+- and Cl−-dependent neurotransmitter transporter gene family (SLC6) with a high homology to GAT1 (SLC6A1), GAT2 (SLC6A13) and GAT3 (SLC6A11). They have 12 hydrophobic transmembrane domains (TMDs), a large extracellular loop between TMD3 and 4 with multiple glycosylation sites, and intracellular N- and C-termini.nBGT1 expression may vary among species. In the dog, BGT1 mRNA is primarily detected in the kidney while the levels in the brain and liver are considerably lower. The highest BGT1 mRNA levels in the mouse are in the liver, while the highest levels in man are in the kidney followed by the liver3. BGT-1 is also present in the brain, but appears to be at low levels and mostly in the leptomeninges rather than in brain tissue proper.nHomozygous BGT1-deficient mice have normal development and show seizure susceptibility indistinguishable from that in wild-type mice in a variety of seizure threshold models.
- 应用类型
- 经验证，该抗体可应用于WB等实验应用，也可用于IC、IFC、IH、IP等实验。
- 免疫原
- Betaine/GABA Transporter 1 (BGT-1)抗体的免疫原肽段为(C)GEMMDQKDKDQVKD。此免疫原序列来源于22- 35 位氨基酸残基，该序列来源于大鼠Betaine/GABA Transporter 1 (Accession编号为P48056)。胞内, N端
- 来源宿主
- 兔
- 反应性
- 反应性：小鼠、 大鼠
- 保存建议
- 艾美捷为您提供的Betaine/GABA Transporter 1 (BGT-1)抗体(25 ul)为室温运输，建议您收到产品后﹣20℃保存。
- 其他
- Alomone成立于1989年,已经成为全世界科学家信赖的最全面的离子通道研究工具供应商。产品覆盖离子通道、G蛋白耦联受体和神经信号研究所需的一抗、小分子、蛋白质和多肽等。所有Alomone产品均进行了生物实验验证，以冻干粉形式提供，可确保产品生物活性和保质期。Alomone可提供多种包装规格，灵活方便。作为Alomone Labs在中国的区域总代理，艾美捷科技有限公司将为中国客户提供最全面的Alomone Labs产品以及客户订制化服务。
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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