- 中文名称
催乳素 ELISA
- 英文名字
- Prolactin ELISA
- 供应商
- Ansh Labs
- 产品货号
- AL-199
- 产品报价
- ¥询价/96wellmicrotiter

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- Prolactin is a 198-amino acid, 23 kDa polypeptide hormone secreted in significant amounts by the anterior pituitary gland. The prolactin molecule has extensive sequence homology with growth hormone and placental lactogen1. Recent studies have revealed molecular heterogeneity for prolactin in both pituitary extracts and blood2,3. Prolactin secretion is regulated by complex mechanisms involving neurotransmitters and endocrine hormones. Many of the regulatory pathways involve hypothalamic secretion of dopamine, which inhibits prolactin secretion4. Prolactin, in synergy with estrogen, plays an important physiologic role in the initiation and maintenance of mammary land growth and lactation in humans1,4.
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nIn addition, prolactin may have effects on cell growth in other tissues and on immune function. Particularly when present in high concentrations, prolactin may have inhibitory effects on gonadal function. Prolactin is present in several body fluids, including plasma, amniotic fluid, milk, mucosal secretions, and cerebrospinal fluid. Relative elevations in plasma prolactin concentrations occur during ovulation, pregnancy, nursing and stress1,2,4. Abnormal elevations in plasma prolactin levels, or hyperprolactinemia, can occur as a result of pituitary adenomas, and may also be seen in other anatomic and traumatic abnormalities involving the pituitary gland (e.g., tumors, surgery, trauma), as a consequence of certain pharmacologic agents, and primary hypothyroidism. Low prolactin levels, or hypoprolactinemia, is observed in cases of hypopituitarism5,6.
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nReferences:
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n - Nicoll CS, Mayer GL, Russell SM: Structural features of prolactins and growth hormones that can be related to their biological properties. Endocrin Rev 7:169-203, 1986.
n - Sinha YN: Structural variants of prolactin: occurrence and physiological significance. Endocrin Rev 16:354-369, 1995.
n - Liu MY, Zhou S, Tang T: Radioreceptor assay for human prolactin and the heterogeneity of prolactin in the sera from patients with pituitary prolactin-secreting adenoma. Chin J Pathophysiol 10:420, 1994.
n - Lambert SWJ, MacLeod RM: Regulation of prolactin secretion at the level of the lactotroph. Physiol Rev 70:219-318, 1990.
n - Liu MY, Zhou S: The new aspects of prolactin action. Prog Physiol Sci 21:36, 1990.s et al: Measurement of serum ferritin by a two-site immunoradiometric assay. Ann Biochem 61:209, 1974.
n - Burtis CA,Ashwood ER: Tietz Textbook of Clinical Chemistry, 2nd ed. W.B. Saunders Company, Philadelphia, 1994, p 1675.
n - HHS Publication, 5th ed., 2007. Biosafety in Microbiological and Biomedical Laboratories. Available http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5
n - DHHS (NIOSH) Publication No. 78–127, August 1976. Current Intelligence Bulletin 13 - Explosive Azide Hazard. Available: http:// www.cdc.gov/niosh.
n - Kricka L. Interferences in immunoassays – still a threat. Clin Chem 2000; 46: 1037–1038.
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- 产品描述
- Prolactin Enzyme-Linked Immunosorbent Assay (ELISA) Kit provides materials for the quantitative measurement of prolactin in human serum.
- 产品特点
- 保存建议
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是开发和生产免疫检测试剂盒和定制生物技术检测产领创者,总部位于美国休斯敦,公司产品遍及全球80多个国家。公司于2011年成立,核心团队来自于Diagnostic system laboratory,专注于女性健康和激素检测领域近40年,拥有全球领先的核心技术, 以及多年经验生物技术研发经验的科学家团队,产品覆盖生殖健康,高危妊娠,肿瘤,糖尿病等多个疾病领域,围绕最新的免疫分析技术,多种蛋白和单克隆抗体,如AMH,BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等几十余种试剂产品,也同时涵盖小鼠,大鼠,狗,羊,牛等灵长类多个物种的独特的物种特异性的试剂。
Ansh labs 坐落于美国德克萨斯州,是目前世界上唯一能提供TGF-β超家族所有成员的检测公司,也是最早专注激素类产品研究和新型免疫检测技术的先驱者。优势产品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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- 注意
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