- 中文名称
卵泡抑素样 3 ELISA
- 英文名字
- Follistatin-Like 3 ELISA
- 供应商
- Ansh Labs
- 产品货号
- AL-152
- 产品报价
- ￥询价/96wellmicrotiter
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Follistatin-like 3 (FSTL-3), also known as Follistatin-related Gene (FLRG) and Follistatin-related protein (FSRP), is a 30-35 kDa secreted glycoprotein. FSTL-3 encodes a novel secreted glycoprotein that is highly homologous to follistatin and binds activins and bone morphogenetic proteins, members of the TGF beta superfamily of growth/differentiation factors. FSTL-3 protein inhibits activin-induced and bone morphogenetic protein-2-induced transcriptional responses in a dose-dependent manner, and its mRNA is abundantly expressed in human placenta, trophoblast, heart, uterus, ovary, testis and adrenal gland. Mature human FSTL-3 consists of an Activin and Myostatin binding N-terminal domain, two Follistatin-like domains, and two Kazal-like domains. BMP-2, -6, and -7 do not compete for Activin A binding, and FSTL-3 binds only weakly to Activin B. Unlike Follistatin, FSTL-3 does not contain a heparin-binding domain and does not interact with heparin sulfate proteoglycans. FSTL-3 has been studied in regulation of energy balance and metabolism, gestational diabetes, preeclampsia, and promotor of tumor cell proliferation.
n
nReferences
n1. Peiris, H.N. et al. (2010) Am. J. Physiol. Endocrinol. Metab. 298:E854.
n2. Biron-Shental, T. et al. (2008) Placenta 29:51.
n3. Lara-Pezzi et al., (2008) Endocrinology 149(11):5822
n3. Florio, P. et al. (2004) Mol. Cell. Endocrinol. 218:129.
n4. Wang, H.Q. et al. (2003) J. Clin. Endocrinol. Metab. 88:4432
n5. Shi, F.-T. et al. (2011) PLoS ONE 6:e22866.
n6. Liu, J. et al. (2002) Mol. Hum. Reprod. 8:992.
n7. Xia, Y. et al. (2004) Mol. Endocrinol. 18:979.
n8. Xia, Y. and A.L. Schneyer (2009) J. Endocrinol. 202:1.
n9. Hayette, S. et al. (1998) Oncogene 16:2949.
n10. Stamler, R. et al. (2008) J. Biol. Chem. 283:32831.
n11. Cash, J.N. et al. (2012) J. Biol. Chem. 287:1043.
n12. Hill, J. et al. (2002) J. Biol. Chem. 277:40735.
n13. Schneyer, A. et al. (2003) Endocrinology 144:1671
n14. Sidis, Y. et al. (2006) Endocrinology 147:3586. 8. Sidis, Y. et al. (2002) Endocrinology 143:1613.
n15. Sidis, Y. et al. (2005) Endocrinology 146:130.
n16. Saito, S. et al. (2005) Endocrinology 146:5052.
n17. Mukherjee, A. et al. (2007) Proc. Natl. Acad. Sci. 104:1348.
n18. Hu, D. et al. (2012) Clin. Chim. Acta 413:533.
n19. Thadhani, R. et al. (2010) Diabetes Care 33:664.
- 产品描述
- The FSTL-3 enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of FSTL-3 in human serum.
- 产品特点
- 保存建议
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是开发和生产免疫检测试剂盒和定制生物技术检测产领创者，总部位于美国休斯敦，公司产品遍及全球80多个国家。公司于2011年成立，核心团队来自于Diagnostic system laboratory，专注于女性健康和激素检测领域近40年，拥有全球领先的核心技术， 以及多年经验生物技术研发经验的科学家团队，产品覆盖生殖健康，高危妊娠，肿瘤，糖尿病等多个疾病领域，围绕最新的免疫分析技术，多种蛋白和单克隆抗体，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等几十余种试剂产品，也同时涵盖小鼠，大鼠，狗，羊，牛等灵长类多个物种的独特的物种特异性的试剂。
Ansh labs 坐落于美国德克萨斯州，是目前世界上唯一能提供TGF-β超家族所有成员的检测公司，也是最早专注激素类产品研究和新型免疫检测技术的先驱者。优势产品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
-
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
-
