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ELISA试剂盒
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中文名称

PAPP-A2 ELISA (CE)

英文名字
PAPP-A2 ELISA (CE)
供应商
Ansh Labs
产品货号
AL-109-i
产品报价
¥询价/96wellmicrotiter
产品说明书
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购买方式
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产品新闻
背景资料
Pregnancy associated plasma protein-A2 (PAPP-A2) is a novel metalloproteinase identified as a homolog of PAPP-A in the metzincin superfamily of pappalysins1-8. PAPP-A2 shares 46% sequence identity with PAPP-A3. PAPP-A2 is a noncovalently linked dimer of two 220-kDa subunits. It exhibits robust proteolytic activity against IGFBP-5 and possibly also IGFBP-3 3, 8. PAPP-A2 is expressed in a wide range of tissues and is abundant in placental syncytiotrophoblasts and the pregnant uterus3. The physiological importance of PAPP-A2 is not known.
n
nReferences:
n1. Bulut I, Coskun A, Ciftci A et al. Relationship between Pregnancy-associated plasma protein A and lung cancer. The American Journal of the Medical sciences. April 2009; 337 (4): 241-244
n2. Schindler AM and Bischof B. Histochemical localization of pregnancy associated plasma protein-A in fetal, infant, and adult organs and camparison between sntisera. Gynecol Obstet Invest 1984; 18: 88-94.
n3. Overgaard MT, Oxvig C, Christiansen M , et al. Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the preform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissue. Biol Reprod 1999; 61:1083-1089.
n4. Fialova L, Kalousova M, Soukupova J, et. Al. Relationship of pregnancy associated plasma protein A to renal function and dialysis modalities. Kidney Blood Press Res 2004; 27: 88-95.
n5. Coskum A, Balbay O, Duran S et al. Pregnancy-associated plasma protein A and asthama. Adv Ther 2007; 24: 362-367.
n6. Coskum A, Duran S, Apaydin S, et al. Pregnancy-associated plasma protein A: evaluation of a new biomarker in renal transplanted patients. Transplant Proc 2007; 39:3072-3076.
n7. Bayes-Genis A, Conover CA, Overgaard MT, et al. Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N Engl J Med 2001; 345: 1022-1029.
n8. Overgaard MT, Boldt HB, Laursen LS, Sottrup-Jensen L, Conover CA, Oxvig C. Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase. J Biol Chem 2001; 276:21849-21853.
n9. HHS Publication, 5th ed., 2007. Biosafety in Microbiological and Biomedical Laboratories. Available http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5
n10. DHHS (NIOSH) Publication No. 78–127, August 1976. Current Intelligence Bulletin 13 - Explosive Azide Hazard. Available http:// www.cdc.gov/niosh.
n11. Approved Guideline – Procedures for the Handling and Processing of Blood Specimens, H18-A3. 2004. Clinical and Laboratory Standards Institute.
n12. Kricka L. Interferences in immunoassays – still a threat. Clin Chem 2000; 46: 1037–1038.
产品描述
The PAPP-A2 enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of PAPP-A2 in human serum and other biological fluids.
产品特点
保存建议
Store at 2 to 8°C until expiration date.
其他
Ansh labs是开发和生产免疫检测试剂盒和定制生物技术检测产领创者,总部位于美国休斯敦,公司产品遍及全球80多个国家。公司于2011年成立,核心团队来自于Diagnostic system laboratory,专注于女性健康和激素检测领域近40年,拥有全球领先的核心技术, 以及多年经验生物技术研发经验的科学家团队,产品覆盖生殖健康,高危妊娠,肿瘤,糖尿病等多个疾病领域,围绕最新的免疫分析技术,多种蛋白和单克隆抗体,如AMH,BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等几十余种试剂产品,也同时涵盖小鼠,大鼠,狗,羊,牛等灵长类多个物种的独特的物种特异性的试剂。 Ansh labs 坐落于美国德克萨斯州,是目前世界上唯一能提供TGF-β超家族所有成员的检测公司,也是最早专注激素类产品研究和新型免疫检测技术的先驱者。优势产品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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