- 中文名称
GIP，全 ELISA
- 英文名字
- GIP, Total ELISA
- 供应商
- Ansh Labs
- 产品货号
- AL-1013
- 产品报价
- ￥询价/96wellmicrotiter
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Glucose-dependent insulinotropic polypeptide (GIP) (also known as gastric inhibitory polypeptide) is an incretin hormone produced in the upper gut and secreted to the circulation in response to the ingestion of foods, especially fatty foods(1). It is a peptide hormone consisting of 42 amino acids and derives from posttranslational processing of pre-pro-GIP, a protein consisting of 153 amino acids. It is structurally similar to members of the secretin/glucagon family that include secretin, glucagon, vasoactive intestinal peptide, and growth hormone-releasing factor(2). Growing evidence supports the physiological and pharmacological relevance of GIP in development of obesity and the pathogenesis of cardiovascular disease in addition to its involvement in type 2 diabetic pathophysiology(1,3). GIP acts in the entero-insular axis as an anabolic hormone that increases insulin levels, which in return increases the glycogen and fatty acid synthesis and inhibits the breakdown of fat. GIP also has extra pancreatic functions as well as roles in the stomach to reduce acid secretion by the parietal cells. On the bone, GIP has a dual effect as it causes proliferation of osteoblasts as well as inhibits osteoclastic bone resorption. The widespread expression of GIP-R in the brain suggests that GIP might play an essential function in neuro-signaling mechanisms(2).
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nReferences:
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n1. Fukuda M. The Role of GIP Receptor in the CNS for the Pathogenesis of Obesity. Diabetes. 2021;70(9):1929-1937. doi:10.2337/dbi21-0001
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n2. Gupta K, Raja A. Physiology, Gastric Inhibitory Peptide. [Updated 2022 Sep 26]. StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK546653/
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n3. Heimbürger SM, Bergmann NC, Augustin R, Gasbjerg LS, Christensen MB, Knop FK. Glucose-dependent insulinotropic polypeptide (GIP) and cardiovascular disease. Peptides. 2020; 125:170174. doi: https://doi.org/10.1016/j.peptides.2019.170174
- 产品描述
- The Total GIP enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of GIP (1-42aa, 3-42aa and 1-30aa) in human serum, plasma, and other biological fluids. This assay is intended for in vitro research use only.
- 产品特点
- 保存建议
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是开发和生产免疫检测试剂盒和定制生物技术检测产领创者，总部位于美国休斯敦，公司产品遍及全球80多个国家。公司于2011年成立，核心团队来自于Diagnostic system laboratory，专注于女性健康和激素检测领域近40年，拥有全球领先的核心技术， 以及多年经验生物技术研发经验的科学家团队，产品覆盖生殖健康，高危妊娠，肿瘤，糖尿病等多个疾病领域，围绕最新的免疫分析技术，多种蛋白和单克隆抗体，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等几十余种试剂产品，也同时涵盖小鼠，大鼠，狗，羊，牛等灵长类多个物种的独特的物种特异性的试剂。
Ansh labs 坐落于美国德克萨斯州，是目前世界上唯一能提供TGF-β超家族所有成员的检测公司，也是最早专注激素类产品研究和新型免疫检测技术的先驱者。优势产品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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