- 中文名称
卵母细胞成熟质量 （OMQ） 检查抑制素 A ELISA
- 英文名字
- Oocyte Maturation Quality (OMQ) Check Inhibin A ELISA
- 供应商
- Ansh Labs
- 产品货号
- AL-1009
- 产品报价
- ￥询价/96wellmicrotiter
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Inhibins are heterodimeric protein hormones secreted by granulosa cells of the ovary in the female and Sertoli cells of the testis in the male. They selectively suppress the secretion of pituitary follicle stimulating hormone (FSH) and have local paracrine actions in the gonads. The fully processed form of the inhibin molecule has a molecular weight of approximately 32 kD and consists of the two distinct chains (α and β), linked by disulfide bridges. Higher molecular weight forms, with precursor forms of the α-subunit, also occur in follicular fluid and serum. In addition, free α-subunit forms, unassociated with a β-subunit, and lacking inhibin bioactivity, are also present. Inhibin A consists of an α-subunit and βA-subunit.
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nRecently, Inhibin-A and Inhibin-B are emerging as markers for the assessment of developing follicles during ovarian stimulation.1 and can assist with the follicle dynamics. The number of mature oocytes is a key factor in the IVF success. Gonadotropin dosing during ovarian stimulation cycle is a critical step in maximizing the oocytes yield. The serum estradiol and transvaginal ultrasound measurements are currently used as monitoring tools in stimulated cycle. Serum Estradiol levels are commonly supraphysiological and often variable due to multi-follicular growth of varying size of follicles in IVF cycles. Additionally, Estradiol binds to peripheral SHBG and the competitive nature of the immunoassay makes Estradiol measurement unreliable for checking the oocyte maturation quality. In contrast, serum Inhibin A levels increase only when follicle size are between 12–15 mm. This makes serum Inhibin-A a better marker for studying the Oocyte quality. Along with routine ultrasound measurements, Inhibin A has been studied for optimal timing of trigger medication with a threshold of ≥10 mature oocytes.1 Serum Inhibin-A levels strongly correlate to the number of follicles ≥15mm and mature oocytes. Measurements of Inhibin-A are shown to be useful in studying its role in human reproductive physiology.1
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nReference:
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n1 Barbara Lawrenz, Leyla Depret Bixio, Carol Coughlan, Claus Yding Andersen, Laura Melado, Bhanu Kalra, Gopal Savjani, Human M. Fatemi and Ajay Kumar; Inhibin A- A promising predictive parameter for determination of final oocyte maturation in ovarian stimulation for IVF/ICSI (2020)
- 产品描述
- The Oocyte Maturation Quality (OMQ) Check enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of dimeric Inhibin A in human serum.
- 产品特点
- 保存建议
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是开发和生产免疫检测试剂盒和定制生物技术检测产领创者，总部位于美国休斯敦，公司产品遍及全球80多个国家。公司于2011年成立，核心团队来自于Diagnostic system laboratory，专注于女性健康和激素检测领域近40年，拥有全球领先的核心技术， 以及多年经验生物技术研发经验的科学家团队，产品覆盖生殖健康，高危妊娠，肿瘤，糖尿病等多个疾病领域，围绕最新的免疫分析技术，多种蛋白和单克隆抗体，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等几十余种试剂产品，也同时涵盖小鼠，大鼠，狗，羊，牛等灵长类多个物种的独特的物种特异性的试剂。
Ansh labs 坐落于美国德克萨斯州，是目前世界上唯一能提供TGF-β超家族所有成员的检测公司，也是最早专注激素类产品研究和新型免疫检测技术的先驱者。优势产品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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