- 中文名称
picoIL-6 ELISA
- 英文名字
- picoIL-6 ELISA
- 供应商
- Ansh Labs
- 产品货号
- AL-1007-r
- 产品报价
- ￥询价/96wellmicrotiter
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Interleukin-6 (IL-6) is a member of the IL-6 superfamily, which consists of polypeptide cytokines with a four-α-helix structure and a molecular mass of 21 to 28 kDa. It is produced by the lymphoid and non-lymphoid cells with pleotropic functions ranging from hematopoiesis and metabolic regulation to inflammation, autoimmunity, and acute phase response.
nUnder normal conditions, IL-6 plays an important role in cellular homeostasis. However, during inflammatory conditions, the concentration of IL-6 increases in several folds. This relates its clinical relevance as a major alarm signal in humans in response to infections (sepsis/septicemia), inflammation, autoimmunity, and cancer.1-3 Increased concentrations of IL-6 have been reported in localized (prosthetic joint infections, periodontitis), and systemic (eg, sepsis, coronavirus 2019 [COVID-19]) infections, autoimmune conditions (eg, rheumatoid arthritis (RA), systemic lupus erythematosus, ankylosing spondylitis, and inflammatory bowel disease), and cancers. 3-7 Overall, IL-6 cytokine is nonspecific biomarker of systemic inflammation that may have relevance in clinical decision making in the appropriate context.
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nReferences:
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n1. Rose-John S: Interleukin-6 signalling in health and disease. F1000Res. 2020 Aug 20;9: F1000 Faculty Rev-1013.
n2. Jones SA, Jenkins BJ: Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer. Nat Rev Immunol. 2018; 18:773-89
n3. Rose-John S, Winthrop K, Calabrese L: The role of IL-6 in host defence against infections: immunobiology and clinical implications. Nat Rev Rheumatol. 2017 Jul;13(7):399-409
n4. Gallo J, Svoboda M, Zapletalova J, et al: Serum IL-6 in combination with synovial IL-6/CRP shows excellent diagnostic power to detect hip and knee prosthetic joint infection. PLoS One. 2018;13: e0199226
n5. Song J, Park DW, Moon S, et al: Diagnostic and prognostic value of interleukin-6, pentraxin 3, and procalcitonin levels among sepsis and septic shock patients: a prospective controlled study according to the Sepsis-3 definitions. BMC Infect Dis. 2019; 19:968
n6. Galvan-Roman JM, Rodriguez-Garcia SC, Roy-Vallejo, E, et al: IL-6 serum levels predict severity and response to tocilizumab in COVID-19: An observational study. J Allergy Clin Immunol. 2021; 147:72-80
n7. Udomsinprasert W, Jittikoon J, Sangroongruangsri S, et al: Circulating levels of interleukin-6 and interleukin-10, but not tumor necrosis factor-alpha, as potential biomarkers of severity and mortality for COVID-19: Systematic review with meta-analysis. J Clin Immunol. 2021; 41:11-22
- 产品描述
- The picoIL-6 enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of IL-6 in serum and other biological fluids.
- 产品特点
- 保存建议
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是开发和生产免疫检测试剂盒和定制生物技术检测产领创者，总部位于美国休斯敦，公司产品遍及全球80多个国家。公司于2011年成立，核心团队来自于Diagnostic system laboratory，专注于女性健康和激素检测领域近40年，拥有全球领先的核心技术， 以及多年经验生物技术研发经验的科学家团队，产品覆盖生殖健康，高危妊娠，肿瘤，糖尿病等多个疾病领域，围绕最新的免疫分析技术，多种蛋白和单克隆抗体，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等几十余种试剂产品，也同时涵盖小鼠，大鼠，狗，羊，牛等灵长类多个物种的独特的物种特异性的试剂。
Ansh labs 坐落于美国德克萨斯州，是目前世界上唯一能提供TGF-β超家族所有成员的检测公司，也是最早专注激素类产品研究和新型免疫检测技术的先驱者。优势产品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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