ATP6V1E2 (ATPase H+ Transporting V1 Subunit E2) is a Protein Coding gene. Among its related pathways are Rheumatoid arthritis and mTOR signaling pathway (KEGG). GO annotations related to this gene include proton-transporting ATPase activity, rotational mechanism and hydrogen-exporting ATPase activity, phosphorylative mechanism. Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome.