The protein encoded by TRPC1 (Transient Receptor Potential Cation Channel Subfamily C Member 1) is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for TRPC1.
