TNNC2 (Troponin C2, Fast Skeletal Type) is a Protein Coding gene. Diseases associated with TNNC2 include Distal Arthrogryposis. Among its related pathways are Calcium signaling pathway and Striated Muscle Contraction. Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by TNNC2 is the Tn-C subunit.
