TLX3 (T-Cell Leukemia Homeobox 3) is a Protein Coding gene. Diseases associated with TLX3 include Precursor T-Cell Acute Lymphoblastic Leukemia and T-Cell Leukemia. Among its related pathways are Transcriptional misregulation in cancer and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The protein encoded by TLX3 is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5;14)(q35;q32)] involving TLX3 is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults.
