SYNE2 (Spectrin Repeat Containing Nuclear Envelope Protein 2) is a Protein Coding gene. Diseases associated with SYNE2 include Emery-Dreifuss Muscular Dystrophy 5, Autosomal Dominant and Emery-Dreifuss Muscular Dystrophy 2, Ad. Among its related pathways are Meiosis and Ovarian Infertility Genes. The protein encoded by SYNE2 is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus.