SH3BP4 (SH3 Domain Binding Protein 4) is a Protein Coding gene. Diseases associated with SH3BP4 include Cataract 8, Multiple Types. Among its related pathways are PI3K / Akt Signaling. SH3BP4 encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor.
