FRZB (Frizzled-Related Protein) is a Protein Coding gene. Diseases associated with FRZB include Osteoarthritis 1 and Osteoarthritis. Among its related pathways are Adipogenesis and Endochondral Ossification. The protein encoded by FRZB is a secreted protein that is involved in the regulation of bone development. Defects in FRZB are a cause of female-specific osteoarthritis (OA) susceptibility.