RNF41 encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. RNF41 (Ring Finger Protein 41) is a Protein Coding gene. Among its related pathways are Signaling by ERBB2 and Regulation of lipid metabolism Insulin signaling-generic cascades.
