RPL7A (Ribosomal Protein L7a) is a Protein Coding gene. Diseases associated with RPL7A include Tuberous Sclerosis-1. Among its related pathways are Viral mRNA Translation and Metabolism. RPL7A encodes a ribosomal protein that is a component of the 60S subunit. RPL7A is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity.RPL7A rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of RPL7A dispersed through the genome.
