PCF11 (PCF11 Cleavage And Polyadenylation Factor Subunit) is a Protein Coding gene. Among its related pathways are mRNA surveillance pathway and Formation of HIV elongation complex in the absence of HIV Tat. The protein encoded by PCF11 binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage.
