NPW (Neuropeptide W) is a Protein Coding gene. Diseases associated with NPW include Neurodegeneration With Brain Iron Accumulation 6 and Retinitis Pigmentosa, X-Linked Recessive, 6. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. The product of NPW is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade.
