NMB (Neuromedin B) is a Protein Coding gene. Diseases associated with NMB include Gastrinoma and Neuronal Ceroid Lipofuscinosis. Among its related pathways are Signaling by GPCR and RET signaling. NMB encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of NMB may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants.
