NKX2-3 (NK2 Homeobox 3) is a Protein Coding gene. Diseases associated with NKX2-3 include Crohn's Disease. An important paralog of NKX2-3 is NKX2-5. NKX2-3 encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiation.