NFIX (Nuclear Factor I X) is a Protein Coding gene. Diseases associated with NFIX include Sotos Syndrome 2 and Marshall-Smith Syndrome. Among its related pathways are RNA Polymerase III Transcription Initiation and Gene Expression. The protein encoded by NFIX is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for NFIX.
