The protein encoded by NSMCE3 (NSE3 Homolog, SMC5-SMC6 Complex Component) is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. NSMCE3 is a Protein Coding gene. Diseases associated with NSMCE3 include Lung Disease, Immunodeficiency, And Chromosome Breakage Syndrome and Viral Pneumonia. Among its related pathways are SUMOylation and p75(NTR)-mediated signaling. An important paralog of NSMCE3 is MAGEF1.