LTB4R (Leukotriene B4 Receptor) is a Protein Coding gene. Diseases associated with LTB4R include Image Syndrome. Among its related pathways are Nucleotide-like (purinergic) receptors and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and leukotriene receptor activity. An important paralog of this gene is LTB4R2. Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
