LRP4 (LDL Receptor Related Protein 4) is a Protein Coding gene. Diseases associated with LRP4 include Cenani-Lenz Syndactyly Syndrome and Sclerosteosis 2. Among its related pathways are ECM proteoglycans and Degradation of the extracellular matrix. LRP4 encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in LRP4 are associated with Cenani-Lenz syndrome.